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CHEM 110 Preparation for General Chemistry (3/5) NSc
Introduction to general chemistry with an emphasis on developing problem solving skills. Covers basic concepts of chemistry along with the mathematics required for quantitative problem solving. For students without high school chemistry or with limited mathematics background. Successful completion of CHEM 110 prepares students to enroll in CHEM 142. Prerequisite: assessment of skills by taking the General Chemistry Placement Exam. Offered: AWS.

CHEM 120 Principles of Chemistry I (5) NSc, RSN
First course in a three-quarter overview of general chemistry, organic chemistry, and biochemistry. Not for students majoring in biochemistry, chemistry, or engineering. Includes matter and energy, chemical nomenclature, chemical reactions, stoichiometry, modern atomic theory, chemical bonding. Laboratory. Maximum 6 credits allowed between CHEM 120; CHEM 142; CHEM 143; CHEM 145; B CHEM 115; B CHEM 143; and B CHEM 144. Course equivalent to: B CHEM 115. Course overlaps with: CHEM 142; CHEM 143; and CHEM 145. Prerequisite: assessment of skills by taking General Chemistry Placement Exam. Offered: AS.

CHEM 142 General Chemistry (5) NSc, RSN
For science and engineering majors. Atomic nature of matter, quantum mechanics, ionic and covalent bonding, molecular geometry, stoichiometry, solution stoichiometry, kinetics, and gas laws. Includes laboratory. Maximum 6 credits allowed between CHEM 120; CHEM 142; CHEM 143; CHEM 145; B CHEM 115; B CHEM 143; and B CHEM 144. Course overlaps with: CHEM 120; CHEM 143; CHEM 145; B CHEM 115; B CHEM 143; and T CHEM 142. Prerequisite: either a minimum grade of 1.7 in CHEM 110, a passing score in the General Chemistry Placement exam, or a minimum score of 1 on the Chemistry AP exam; recommended: MATH 120 or MATH 124. Offered: AWSpS.

CHEM 143 Accelerated General Chemistry (6) NSc, RSN
Covers equivalent of half of year-long general chemistry sequence (CHEM 142, CHEM 152, CHEM 162). For science and engineering majors. Stoichiometry, gas laws, atomic structure, quantum mechanics, general bonding, kinetics, gas-phase equilibria, acid-base equilibria, applications of aqueous equilibria. Includes laboratory. Maximum 6 credits allowed between CHEM 120; CHEM 142; CHEM 143; CHEM 145; B CHEM 115; B CHEM 143; and B CHEM 144. Course overlaps with: CHEM 120; CHEM 142; CHEM 145; and B CHEM 115. Prerequisite: either a minimum grade of 1.7 in CHEM 110, a passing score in the General Chemistry Placement exam, or a minimum score of 1 on the Chemistry AP exam; recommended: MATH 120 or MATH 124. Offered: A.

CHEM 145 Honors General Chemistry (5) NSc, RSN
CHEM 145, CHEM 155, and CHEM 165, together, cover the topics in CHEM 142, CHEM 152, and CHEM 162 at a more advanced level and with greater mathematical rigor. Maximum 6 credits allowed between CHEM 120; CHEM 142; CHEM 143; CHEM 145; B CHEM 115; B CHEM 143; and B CHEM 144. Course overlaps with: CHEM 120; CHEM 142; CHEM 143; and B CHEM 115. Prerequisite: either MATH 124 or MATH 134 (either of which may be taken concurrently), a minimum score of 66 on the Honors General Chemistry placement exam (HCHEMC or HCHEMD), a minimum score of 3 on the AP Chemistry exam, or a minimum score of 5 on the IB high level chemistry exam. Offered: A.

CHEM 152 General Chemistry (5) NSc, RSN
Gas phase and aqueous equilibria (with emphasis on acid-base equilibrium), thermochemistry, thermodynamics, and electrochemistry. Includes laboratory. Maximum 6 credits allowed between CHEM 152; CHEM 153; CHEM 155; B CHEM 153; and B CHEM 154. Course overlaps with: CHEM 153; CHEM 155; B CHEM 153; and T CHEM 152. Prerequisite: a minimum grade of 1.7 in either CHEM 142, CHEM 143, or CHEM 145. Offered: AWSpS.

CHEM 153 Accelerated General Chemistry (6) NSc
Continuation of CHEM 143. Covers equivalent of half of year-long general chemistry sequence (CHEM 142, CHEM 152, CHEM 162). For science and engineering majors. Thermodynamics, electrochemistry, bonding, liquids, solid and solutions, transition metals. Includes laboratory. Maximum 6 credits allowed between CHEM 152; CHEM 153; CHEM 155; B CHEM 153; and B CHEM 154. Course overlaps with: CHEM 152 and CHEM 155. Prerequisite: a minimum grade of 2.0 in CHEM 143. Offered: W.

CHEM 155 Honors General Chemistry (5) NSc, RSN
CHEM 145, CHEM 155, and CHEM 165, together, cover the topics in CHEM 142, CHEM 152, and CHEM 162 at a more advanced level and with greater mathematical rigor. Maximum 6 credits allowed between CHEM 152; CHEM 153; CHEM 155; B CHEM 153; and B CHEM 154. Course overlaps with: CHEM 152 and CHEM 153. Prerequisite: a minimum grade of 2.2 in CHEM 145. Offered: W.

CHEM 162 General Chemistry (5) NSc, RSN
Molecular bonding theories, liquids, solids, solutions, and introduction to organic and transition metal chemistry. Includes laboratory. Maximum 6 credits allowed between CHEM 162; CHEM 165; B CHEM 163; and B CHEM 164. Course overlaps with: CHEM 165; B CHEM 163; B CHEM 164; and T CHEM 162. Prerequisite: a minimum grade of 1.7 in CHEM 152. Offered: AWSpS.

CHEM 165 Honors General Chemistry (5) NSc, RSN
CHEM 145, CHEM 155, and CHEM 165, together, cover the topics in CHEM 142, CHEM 152, and CHEM 162 at a more advanced level and with greater mathematical rigor. Maximum 6 credits allowed between CHEM 162; CHEM 165; B CHEM 163; and B CHEM 164. Course overlaps with: CHEM 162. Prerequisite: minimum grade of 2.2 in CHEM 155. Offered: Sp.

CHEM 196 Chemistry Frontiers (1)
Exposes freshmen and new transfer undergraduate students to current topics of U.W. research in chemistry. Students interface with research groups. Includes a "big picture" description of the scientific goals and main questions of the highlighted group along with a discussion of experimental methods. Credit/no-credit only.

CHEM 197 Science Outreach Training (1-2, max. 2)
Training as a peer mentor for General Chemistry or for participation in science-related outreach activities to the community. Not applicable toward chemistry degree requirements. Credit/no-credit only.

CHEM 198 Tutorial Study (2, max. 6)
Credit/no-credit only.

CHEM 199 Special Problems (1-6, max. 6)
Research in chemistry. Credit/no-credit only. Offered: AWSpS.

CHEM 220 Principles of Chemistry II (5) NSc
Second course in a three-quarter overview of general chemistry, organic chemistry, and biochemistry. Not for students majoring in biochemistry, chemistry, or engineering. Introduction to organic chemistry including organic compounds, functional groups, stereochemistry, and basic organic reactions. Course overlaps with: CHEM 223; CHEM 237; CHEM 257; and B CHEM 237. Prerequisite: a minimum grade of 1.7 in either CHEM 120, CHEM 142, or CHEM 143. Offered: W.

CHEM 221 Principles of Chemistry III (5) NSc
Third course in a three-quarter overview of general chemistry, organic chemistry, and biochemistry. Not for students majoring in biochemistry, chemistry, or engineering. Introduction to biochemistry including biomolecular structure, proteins, nucleic acids, biochemical cycles, and cellular energetics. Course overlaps with: CHEM 224; CHEM 239; CHEM 259; and B CHEM 239. Prerequisite: a minimum grade of 1.7 in CHEM 220. Offered: Sp.

CHEM 223 Organic Chemistry - Short Program (4) NSc
First of a two-quarter series. Not for biochemistry or chemistry majors and may not be accepted by professional schools that require organic chemistry. Introduction to structure, nomenclature, properties, and reactions of organic compounds with a focus on alkenes, alkynes, and alkyl halides. Stereochemistry and spectroscopy. Course overlaps with: CHEM 220; CHEM 237; CHEM 257; and B CHEM 237. Prerequisite: a minimum grade of 1.7 in either CHEM 152, CHEM 153, or CHEM 155. Offered: AS.

CHEM 224 Organic Chemistry - Short Program (4) NSc
Continuation of CHEM 223. Structure, nomenclature, properties, and reactions of aldehydes, ketones, carboxylic acid derivatives, amines, carbohydrates, lipids, amino acids, peptides, proteins, and nucleic acids. No laboratory accompanies this course, but CHEM 241 laboratory may be taken concurrently. Course overlaps with: CHEM 221; CHEM 239; CHEM 259; and B CHEM 239. Prerequisite: a minimum grade of 1.7 in CHEM 223. Offered: WS.

CHEM 237 Organic Chemistry (4) NSc
First course for students planning to take three quarters of organic chemistry. Introduction to physical properties, structure, nomenclature, and stereochemistry of organic compounds. Reactions of alkenes and alkynes. No organic laboratory accompanies this course. CHEM 237; CHEM 238; and CHEM 239 (or equivalents) must be completed in sequence. Course equivalent to: B CHEM 237. Course overlaps with: CHEM 220; CHEM 223; CHEM 257; and T CHEM 251. Prerequisite: a minimum grade of 1.7 in either CHEM 153, CHEM 162, or CHEM 165. Offered: AWSpS.

CHEM 238 Organic Chemistry (4) NSc
Second course for students planning to take three quarters of organic chemistry. Further discussion of physical properties and transformations of organic molecules, especially aromatic compounds, and spectroscopy of organic molecules. CHEM 237; CHEM 238; and CHEM 239 (or equivalents) must be completed in sequence. Course equivalent to: B CHEM 238. Course overlaps with: CHEM 258. Prerequisite: a minimum grade of 1.7 in either CHEM 237 or CHEM 257. Offered: AWSpS.

CHEM 239 Organic Chemistry (4) NSc
Third course for students who take three quarters of organic chemistry. Further discussion of physical properties and transformations of organic molecules, especially carbonyl compounds and amines. Polyfunctional compounds and biological polymers including carbohydrates, amino acids, proteins, and nucleic acids. CHEM 237; CHEM 238; and CHEM 239 (or equivalents) must be completed in sequence. Course equivalent to: B CHEM 239. Course overlaps with: CHEM 221; CHEM 224; CHEM 259; and T CHEM 271. Prerequisite: a minimum grade of 1.7 in either CHEM 238 or CHEM 258. Offered: AWSpS.

CHEM 241 Organic Chemistry Laboratory (3) NSc
Introduction to organic laboratory techniques. Synthesis, purification, and spectroscopic analysis of representative compounds. Designed to be taken with CHEM 224 or CHEM 238. Course equivalent to: B CHEM 241. Course overlaps with: CHEM 261. Prerequisite: a minimum grade of 1.7 in either CHEM 223, CHEM 237, or CHEM 257; and a minimum grade of 1.7 in either CHEM 224, CHEM 238, or CHEM 258, any of which may be taken concurrently. Offered: AWSpS.

CHEM 242 Organic Chemistry Laboratory (3) NSc
Preparations and qualitative organic analysis. Designed to be taken with CHEM 239. Course equivalent to: B CHEM 242. Course overlaps with: CHEM 262. Prerequisite: a minimum 1.7 grade in either CHEM 241 or CHEM 261; a minimum grade of 1.7 in either CHEM 223, CHEM 238, or CHEM 258; and a minimum grade of 1.7 in either CHEM 224, CHEM 239 (which may be taken concurrently), or CHEM 259 (which may be taken concurrently). Offered: AWSpS.

CHEM 257 Honors Organic Chemistry (4) NSc
For chemistry majors and otherwise qualified students planning three or more quarters of organic chemistry. Structure, nomenclature, reactions, and synthesis of organic compounds. Theory and mechanism of organic reactions. Studies of biomolecules. No organic laboratory accompanies this course. Course overlaps with: CHEM 220; CHEM 223; CHEM 237; and B CHEM 237. Prerequisite: either CHEM 153, CHEM 162, or CHEM 165. Offered: A.

CHEM 258 Honors Organic Chemistry (4) NSc
For chemistry majors and otherwise qualified students planning three or more quarters of organic chemistry. Structure, nomenclature, reactions, and synthesis of organic compounds. Theory and mechanism of organic reactions. Studies of biomolecules. Course overlaps with: CHEM 238 and B CHEM 238. Prerequisite: a minimum grade of 2.2 in CHEM 257. Offered: W.

CHEM 259 Honors Organic Chemistry (4) NSc
For chemistry majors and other qualified students. Structure, reactions, and synthesis of organic compounds. Discussion of physical properties and transformations of molecules such as enols, enolates, amines, and phenols. Polyfunctional compounds and biological polymers (e.g., carbohydrates, amino acids, proteins, and nucleic acids). Course overlaps with: CHEM 221; CHEM 224; CHEM 239; and B CHEM 239. Prerequisite: a minimum grade of 2.2 in CHEM 258. Offered: Sp.

CHEM 261 Honors Organic Chemistry Laboratory (3) NSc
Introduction to organic laboratory techniques. Preparation, purification, and analytical characterization of organic compounds. Designed to be taken with CHEM 258. Course overlaps with: CHEM 241 and B CHEM 241. Prerequisite: a minimum grade of 1.7 in CHEM 257; and a minimum grade of 1.7 in CHEM 258, which may be taken concurrently. Offered: W.

CHEM 262 Honors Organic Chemistry Laboratory (3) NSc
Synthetic preparation and qualitative analysis of organic molecules and biomolecules. Designed to accompany CHEM 259. Course overlaps with: CHEM 242 and B CHEM 242. Prerequisite: a minimum grade of 1.7 in CHEM 258; a minimum grade of 2.2 in CHEM 261; and a minimum 1.7 grade in CHEM 259, which may be taken concurrently. Offered: Sp.

CHEM 291 Study Abroad - Chemistry (1-15, max. 15) NSc
For student in the UW study abroad program. Content varies and is individually evaluated. Credit does not apply to major degree requirements without departmental approval.

CHEM 297 Science Outreach Participation (1/2, max. 6)
Serve as an experienced peer mentor for general Chemistry or as an experienced outreach volunteer. Not applicable toward chemistry degree requirements. Prerequisite: CHEM 197 Credit/no-credit only.

CHEM 299 Special Problems and Report Writing (1-6, max. 6)
Research in chemistry and/or study in the chemical literature. Requires writing a scientific report. Credit/no-credit only. Offered: AWSpS.

CHEM 312 Inorganic Chemistry (3) NSc
Introduces principles of inorganic chemistry and its broader relevance in society. Emphasis on bonding, physical properties, and reactivity of transition metal complexes. Prerequisite: either CHEM 153, CHEM 162, or CHEM 165; and either CHEM 224, CHEM 238, or CHEM 258. Offered: AWS.

CHEM 317 Inorganic Chemistry Laboratory (4) NSc
Experimental exploration of the periodic table. Techniques of preparation and characterization of inorganic compounds. Prerequisite: either CHEM 165 or CHEM 312; and either CHEM 242, CHEM 262, or B CHEM 242. Offered: AWSp.

CHEM 321 Quantitative Analysis (5) NSc
Introduction to quantitative chemical analysis, including gravimetric, volumetric, spectrophotometric, and potentiometric analysis, as well as chemical separations and data analysis. Includes laboratory. Course overlaps with: B CHEM 316. Prerequisite: either CHEM 153, CHEM 162, or CHEM 165. Offered: AWSpS.

CHEM 397 Science Outreach Mentors (1-2, max. 6)
Credit/no-credit only.

CHEM 399 Undergraduate Research (*, max. 12)
Research in chemistry. Credit/no-credit only. Offered: AWSpS.

CHEM 416 Transition Metals (3) NSc
Survey of selected key topics in the chemistry of the transition metals, including emphasis on the structure, bonding, and reactivity of major classes of compounds. Prerequisite: either CHEM 165 or CHEM 312; recommended: CHEM 312. Offered: A.

CHEM 417 Organometallic Chemistry (3) NSc
Chemistry of the metal-carbon bond for both main group and transition metals. Structure and reactivity with applications to organic synthesis and catalysis. Prerequisite: either CHEM 224, CHEM 239, CHEM 259, or B CHEM 239; and CHEM 312. Offered: W.

CHEM 418 Nuclear Chemistry (3) NSc
Natural radioactivity, nuclear systematics and reactions, radioactive decay processes, stellar nucleosynthesis, applications of radioactivity. Prerequisite: either CHEM 453, CHEM 455, or CHEM 475. Offered: W.

CHEM 422 Analytical Spectroscopy (3) NSc
Qualitative and quantitative analysis of molecular species, using various optical spectroscopy techniques including absorption, fluorescence, Raman, and advanced nonlinear optical spectroscopy. Prerequisite: CHEM 321; and CHEM 455 or CHEM 475, either of which may be taken concurrently. Offered: A.

CHEM 425 Meso and Microfluidics in Chemical Analysis (3) NSc
Covers chemical, biological, and medical applications of micro- and mesofluidics. Topics include fundamentals, droplet-based microfluidics, cell based assays and 'organ on a chip' models, analytical methods using microfluidics, open microfluidics, and microfabrication/surface chemistry. Prerequisite: either CHEM 153, CHEM 162, or CHEM 165. Offered: Sp.

CHEM 426 Instrumental Analysis (3) NSc
Introduction to modern instrumental methods of chemical analysis, including chromatography, optical and mass spectroscopy, electrochemistry and flow injection analysis. Basic concepts of transducers, spectrometers, mass analysis, separation sciences, and computerized data acquisition and reduction. Includes laboratory. Prerequisite: CHEM 321. Offered: W.

CHEM 428 Biomolecular Analysis (3) NSc
Principles of identifying and quantifying biological molecules, including metabolites, proteins, and nucleic acids, using modern analysis techniques, including analytical spectroscopy, molecular recognition, mass spectrometry, and separations. Emphasis on bioinformatics as well as the role of chemical measurements in medical diagnostics and biomedical research. Includes laboratory. Prerequisite: either BIOC 405, BIOC 440, or CHEM 321 Offered: Sp.

CHEM 429 Chemical Separation Techniques (3) NSc
Introduction to modern separation techniques such as gas chromatography, high-performance liquid chromatography, electrophoresis, and field flow fractionation. Prerequisite: either CHEM 224, CHEM 239, CHEM 259, or B CHEM 239; and either CHEM 241, CHEM 321, CHEM 261, or B CHEM 241. Offered: W.

CHEM 430 Advanced Physical Organic Chemistry (3) NSc
Fundamental aspects of organic structures and transformations with an emphasis on frontier molecular orbital theory and arrow-pushing mechanisms. Structure and reactivity of carbocations, addition reactions, substitution reactions, elimination reactions, structure and reactivity of anions, electrophilic substitutions, neighboring group effects, conformational analysis, pericyclic reactions, and single-electron chemistry. Prerequisite: either CHEM 239, CHEM 259, or B CHEM 239. Offered: A.

CHEM 431 Advanced Synthetic Organic Chemistry (3) NSc
Synthetic organic chemistry. Discussion of practical methods for the synthesis of complex organic molecules with an emphasis on strategy and the control of stereochemistry. Prerequisite: CHEM 430. Offered: W.

CHEM 432 Advanced Bio-Organic Chemistry (3) NSc
Fundamental aspects of the structure, function, and synthesis of biological molecules. Enzyme mechanisms with an emphasis on cofactor-dependent and redox catalysis, and applications of biological catalysts in organic synthesis. Biological synthesis of complex organic molecules. Application of chemical methods to the study of biological processes. Prerequisite: either CHEM 239, CHEM 259, or B CHEM 239; and CHEM 242 or CHEM 262. Offered: Sp.

CHEM 434 Polymer Chemistry (3) NSc
Focuses on the fundamental and applied aspects of polymer chemistry with a particular focus on polymer structure, synthesis, and self-assembly. Topics include classic methods and mechanisms for macromolecular synthesis and contemporary breakthroughs in the field and the applications of polymers and their societal impact. Prerequisite: CHEM 239, CHEM 259, or B CHEM 239. Offered: A.

CHEM 436 Chemical Biology (3) NSc
Mechanistic enzymology and chemical biology. Topics include protein structure and function, how enzymes work as catalysts, kinetic methods, functional assays, and applications to current research. Prerequisite: either CHEM 224, CHEM 239, CHEM 259, or B CHEM 239; recommended: either BIOC 405 or BIOC 440 Offered: W.

CHEM 441 Data Science and Materials Informatics (3)
Introduction to data science approaches and their applications to materials science research. Basic skills in data mining, data processing, and machine learning for materials research topics using Python taught through case studies and other methodologies. Recommended: prior programming experience; some experience with Python helpful. Offered: jointly with MSE 477; A.

CHEM 442 Materials and Device Modeling (3)
Implementation of computational and data science methods in materials science discovery and device modeling to gain physical and statistical insights of materials design. First-principles methods, multiscale simulations, and continuum modeling will be introduced within the framework of active machine learning with application of both computational and data science methods to materials study. Prerequisite: MSE 477/CHEM 441. Offered: jointly with MSE 478.

CHEM 443 Big Data for Materials Science (3)
Introduces the challenges and opportunities of the big data era for materials science and chemistry research. Students will gain basic knowledge and skills of data management using high performance computing, including automated data processing, batch processing, and cloud based computational tools that are suitable for materials science research. Prerequisite: MSE 477/CHEM 441. Offered: jointly with MSE 479.

CHEM 452 Thermodynamics and Kinetics for Biochemists (3) NSc
Chemical thermodynamics and kinetics emphasizing biochemical applications. Course overlaps with: CHEM 456 and B CHEM 401. Prerequisite: either CHEM 153, CHEM 162, or CHEM 165; MATH 126 or MATH 136; and PHYS 116 or PHYS 123. Offered: AWS.

CHEM 453 Quantum and Statistical Mechanics for Biochemists (3) NSc
Advanced topics in physical chemistry including quantum mechanics, statistical mechanics, spectroscopy, kinetics, and transport, emphasizing biochemical applications. Course overlaps with: CHEM 455; CHEM 457; CHEM 475; and B CHEM 402. Prerequisite: CHEM 452 or CHEM 456; MATH 126 or MATH 135; and PHYS 116 or PHYS 123. Offered: WSpS.

CHEM 455 Quantum Mechanics of Atoms and Molecules (3) NSc
Foundations of quantum mechanics and applications to atoms and molecules and their spectra. Course overlaps with: CHEM 453; CHEM 475; and CHEM E 456. Prerequisite: either CHEM 153, CHEM 162, or CHEM 165; MATH 126 or MATH 136; and PHYS 116 or PHYS 123. Offered: ASp.

CHEM 456 Chemical Thermodynamics (3) NSc
Chemical thermodynamics. Laws of thermodynamics presented with applications to phase equilibria, chemical equilibria, and solutions. Course overlaps with: CHEM 452. Prerequisite: either CHEM 153, CHEM 162, or CHEM 165; MATH 126 or MATH 136; and PHYS 116 or PHYS 123. Offered: WS.

CHEM 457 Statistical Mechanics of Atoms, Molecules, and Materials (3) NSc
Introduction to statistical mechanics, kinetic theory, transport, and chemical kinetics. Course overlaps with: CHEM 453. Prerequisite: CHEM 455 or CHEM 475; and either CHEM 452, CHEM 456, or CHEM E 326. Offered: SpS.

CHEM 458 Air Pollution Chemistry (4) NSc
Global atmosphere as a chemical system emphasizing physical factors and chemical processes that give rise to elevated surface ozone, particulate matter, and air toxics; international issues of air pollution transport and changing tropospheric background composition; and regulatory control strategies and challenges. Aimed at science and engineering majors. Course overlaps with: B CHEM 350. Offered: jointly with ATM S 458; A.

CHEM 460 Spectroscopic Molecular Identification (3) NSc
Basic theory of spectral techniques - infrared and ultraviolet/visible spectroscopy, NMR, and mass spectrometry - with emphasis on spectral interpretation skills needed for the elucidation of structure, conformation, and dynamics in organic and biological chemistry. Prerequisite: either CHEM 224, CHEM 239, CHEM 259, or B CHEM 239. Offered: A.

CHEM 461 Physical Chemistry Laboratory (3) NSc
Physical measurements in chemistry. Vacuum techniques, calorimetry, spectroscopic methods, electrical measurements. Prerequisite: either CHEM 453, or both CHEM 455 and CHEM 456, or both CHEM 456 and CHEM 475. Offered: ASp.

CHEM 462 Techniques of Synthetic Organic Chemistry (2-3) NSc
Laboratory techniques of synthetic organic chemistry. Vacuum distillation, multistep synthesis, air sensitive reagents, photochemistry, chromatography, and separation techniques. Prerequisite: either CHEM 242, CHEM 347, or B CHEM 242; CHEM 460 which may be taken concurrently. Offered: A.

CHEM 463 Spectroscopic Techniques for Structural Identification (2) NSc
Laboratory techniques of spectroscopic analysis for structural determination and molecular interaction of small molecules using UV, IR, NMR, and mass spectrometry. Prerequisite: CHEM 460. Offered: W.

CHEM 464 Computers in Data Acquisition and Analysis (3) NSc
Introduction to use of the computer in the chemistry laboratory. Principles of microcomputers and their use for such problems as data acquisition, noise reduction, and instrument control. Prerequisite: either CHEM 453, CHEM 455, or CHEM 475; and either MATH 136, or MATH 207 and MATH 208. Offered: Sp.

CHEM 465 Computational Chemistry (3) NSc
Basics of molecular quantum chemistry (Hartree-Fock and density functional theory); numerical implementation using computers, including basics of programming and scientific computing; applications to problems in chemistry; use of computational chemistry software packages to study chemical reactions and molecular properties. Prerequisite: CHEM 455 or CHEM 475. Offered: W.

CHEM 466 Energy Materials, Devices, and Systems (3)
Provides project-based training for synthesis and characterization of new energy materials for generation and storage and integrating renewables into energy systems. Employs instruments at the Clean Energy Research Training Testbeds, a UW user facility. Topics include nanoparticle synthesis, solar cell and module characterization, coin cell battery assembly and testing, photochemistry, 2D semiconductors, and grid simulation. Prerequisite: either PHYS 431, E E 421, MSE 311, MSE 312, MSE 313, MSE 351, MSE 352, CHEM E 456, CHEM 455, or CHEM 475, any of which may be taken concurrently. Offered: jointly with CHEM E 440/MSE 466/PHYS 466; A.

CHEM 475 Honors Quantum Mechanics of Atoms and Molecules (3) NSc
Origins and basic postulates of quantum mechanics, solutions to single-particle problems, angular momentum and hydrogenic wave functions, matrix methods, perturbation theory, variational methods. Covers quantum mechanics at greater depth than CHEM 455. Course overlaps with: CHEM 453 and CHEM 455. Prerequisite: either CHEM 153, CHEM 162, or CHEM 165; MATH 126 or MATH 136; and PHYS 116 or PHYS 123. Offered: A.

CHEM 484 Electronic and Optoelectronic Polymers (3) NSc
Covers the chemistry, physics, materials science, and applications of semiconducting and metallic conjugated polymers. Examines the structural origins of the diverse electronic and optoelectronic properties of conjugated polymers. Exemplifies applications by light-emitting diodes, lasers, solar cells, thin film transistors, electrochromic devices, biosensors, and batteries. Prerequisite: either CHEM 453 or CHEM 455. Offered: jointly with MSE 484; A.

CHEM 485 Electronic Structure and Application of Materials (3) NSc
Introduction to electronic structure theory of solids from a chemical perspective, including band theory and the free electron model, with an emphasis on modern trends in research in inorganic materials in the bulk and on the nanometer scale. Prerequisite: CHEM 455 or CHEM 475; recommended: familiarity with particle in a box; free electron model; symmetry and symmetry elements; molecular orbital theory; principles of inorganic chemistry; and ability to independently research and learn advanced topics. Offered: W.

CHEM 486 Electronic Dynamics in Organic and Inorganic Materials (3) NSc
Energy and charge transfer; exciton migration and charge transport; photophysical dynamics in optoelectronic and kinetic processes in electrochemical energy conversion. Prerequisite: either CHEM 453, CHEM 455, CHEM 475, PHYS 324, or CHEM E 456. Offered: Sp.

CHEM 491 Study Abroad - Advanced Chemistry (1-15, max. 15) NSc
For students in the UW study abroad program. Content varies and is individually evaluated. Credit does not apply to major degree requirements without departmental approval.

CHEM 499 Undergraduate Research (1-10, max. 35)
Research in chemistry. Credit/no-credit only. Offered: AWSpS.

CHEM 500 Grant Proposal and Scientific Writing (1)
Introduces steps in compiling a successful grant proposal and writing scientific articles, personal statements, research summaries, and procuring recommendation letters, using the NSF graduate fellowship as a guide. Students gain experience in peer review processes as assessment of current scientific literature. Credit/no-credit only. Offered: A.

CHEM 501 Readings in Chemistry (1, max. 9)
Individual meetings with faculty to discuss readings (journal articles, book chapters, proceedings) in the chemical sciences. Credit/no-credit only. Offered: AWSpS.

CHEM 508 Advanced Inorganic Chemistry (3)
Introduction to physical inorganic chemistry. Topics include group theory, ligand-field theory, and various physical methods for understanding the properties of open-shell metal ions, including vibrational spectroscopies (IR and Raman), electronic absorption spectroscopy, electron paramagnetic resonance (EPR) spectroscopy, and magnetism. Recommended: familiarity with basic quantum mechanics and statistical thermodynamics; symmetry and symmetry elements; and transition-metal chemistry; and ability to independently research and learn advanced topics. Offered: A.

CHEM 510 Current Problems in Inorganic Chemistry (3, max. 9)
Primarily for doctoral candidates in inorganic chemistry. Current topics (e.g., bioinorganic, advanced organometallic, materials and solid state, advanced inorganic spectroscopy). See department for instructor and topics during any particular quarter. Offered: Sp.

CHEM 516 Transition Metals (3)
Survey of selected key topics in the chemistry of the transition metals, including emphasis on the structure, bonding, and reactivity of major classes of compounds. Recommended: working knowledge of general chemistry and introductory inorganic concepts including Lewis structures, metal-ligand coordination, and oxidation state assignments. Offered: A.

CHEM 517 Organometallic Chemistry (3)
Chemistry of the metal-carbon bond for both main group and transition metals. Structure and reactivity with applications to organic synthesis and catalysis. Prerequisite: CHEM 416 or equivalent background. Offered: W.

CHEM 521 Analytical Electrochemistry (3)
Theory and practice of modern electrochemistry with emphasis on instrumentation and applications in chemical analysis.

CHEM 522 Analytical Spectroscopy (3)
Qualitative and quantitative analysis of molecular species, using various optical spectroscopy techniques including absorption, fluorescence, Raman, and advanced nonlinear optical spectroscopy. Prerequisite: CHEM 321; and CHEM 455 or CHEM 475, either of which may be taken concurrently. Offered: W.

CHEM 523 Geochemical Cycles (4)
Descriptive, quantitative aspects of earth as biogeochemical system. Study of equilibria, transport processes, chemical kinetics, biological processes; their application to carbon, sulfur, nitrogen, phosphorus, other elemental cycles. Stability of biogeochemical systems; nature of human perturbations of their dynamics. Prerequisite: permission of instructor. Offered: jointly with ATM S 508/OCEAN 523.

CHEM 524 Analytical Mass Spectrometry (3)
Theory and practice of mass spectrometry with emphasis on ionization methods, mass analyzers, gas-phase ion chemistry, and spectra interpretation. Recommended: basic knowledge of organic and physical chemistry, including thermodynamics and kinetics. Offered: Sp.

CHEM 525 Meso and Microfluidics in Chemical Analysis (3)
Covers chemical, biological, and medical applications of micro- and mesofluidics. Topics include fundamentals, droplet-based microfluidics, cell based assays and 'organ on a chip' models, analytical methods using microfluidics, open microfluidics, and microfabrication/surface chemistry. Offered: Sp.

CHEM 526 Instrumental Analysis (3)
Introduction to both fundamental theory and instrument design of various analytical instruments. Focuses on four major categories of instrumental analysis methods: optical spectroscopy, chromatography, flow injection analysis, and electroanalytical chemistry. Beyond learning basic analytical principles and instrument design, students receive extensive laboratory training in all major analytical methods. Offered: W.

CHEM 528 Biomolecular Analysis (3)
Principles of quantifying and identifying biological molecules, including metabolites, proteins, and nucleic acids, using modern analysis techniques, including analytical spectroscopy, molecular recognition, mass spectrometry, and separations. Emphasis on bioinformatics, the role of chemical measurements in medical diagnostics and biomedical research, and the primary literature. Includes laboratory. Offered: A.

CHEM 529 Chemical Separation Techniques (3)
Introduction to modern separation techniques such as gas chromatography, high-performance liquid chromatography, electrophoresis, and field flow fractionation. Offered: A.

CHEM 530 Advanced Physical Organic Chemistry (3)
Fundamental aspects of organic structures and transformations with an emphasis on frontier molecular orbital theory and arrow-pushing mechanisms. Structure and reactivity of carbocations, addition reactions, substitution reactions, elimination reactions, structure and reactivity of anions, electrophilic substitutions, neighboring group effects, conformational analysis, pericyclic reactions, and single-electron chemistry. Offered: A.

CHEM 531 Advanced Synthetic Organic Chemistry (3)
Synthetic organic chemistry. Discussion of practical methods for the synthesis of complex organic molecules with an emphasis on strategy and the control of stereochemistry. Prerequisite: CHEM 530. Offered: W.

CHEM 532 Advanced Bio-Organic Chemistry (3)
Fundamental aspects of the structure, function, and synthesis of biological molecules. Enzyme mechanisms with an emphasis on cofactor-dependent and redox catalysis, and applications of biological catalysts in organic synthesis. Biological synthesis of complex organic molecules. Application of chemical methods to the study of biological processes. Prerequisite: CHEM 531. Offered: Sp.

CHEM 534 Polymer Chemistry (3)
Focuses on the fundamental and applied aspects of polymer chemistry with a particular focus on polymer structure, synthesis, and self-assembly. Topics include classic methods and mechanisms for macromolecular synthesis and contemporary breakthroughs in the field and the applications of polymers and their societal impact. Offered: A.

CHEM 536 Chemical Biology (3)
Mechanistic enzymology and chemical biology. Topics include protein structure and function, how enzymes work as catalysts, kinetic methods, functional assays, and applications to current research. Recommended: either BIOC 405 or BIOC 440. Offered: W.

CHEM 540 Current Problems in Organic Chemistry (1-3, max. 12)

CHEM 541 Data Science and Materials Informatics (3)
Introduction to data science approaches and their applications to materials science research. Basic skills in data mining, data processing, and machine learning for materials research topics using Python taught through case studies and other methodologies. Recommended: prior programming experience; and some experience with Python helpful. Offered: jointly with MSE 542; A.

CHEM 542 Materials and Device Modeling (3)
Implementation of computational and data science methods in materials science discovery and device modeling to gain physical and statistical insights of materials design. First-principles methods, multiscale simulations, and continuum modeling will be introduced within the framework of active machine learning with application of both computational and data science methods to materials study. Prerequisite: either MSE 477/CHEM 441, MSE 542/CHEM 541, CHEM E 545/CHEM 545/MSE 545, or CHEM E 546/CHEM 546/MSE 546 (or equivalents). Offered: jointly with MSE 543.

CHEM 543 Big Data for Materials Science (3)
Introduces the challenges and opportunities of the big data era for materials science and chemistry research. Students will gain basic knowledge and skills of data management using high performance computing, including automated data processing, batch processing, and cloud based computational tools that are suitable for materials science research. Prerequisite: either MSE 477/CHEM 441, MSE 542/CHEM 541, or both CHEM E 545/MSE 545/CHEM 545 and CHEM E 546/MSE 546/CHEM 546. Offered: jointly with MSE 544; Sp.

CHEM 545 Data Science Methods for Molecular Science and Engineering (3)
Covers fundamentals of machine learning and implementing data science in Python. Introduces modern data science methods taught in the context of molecular science and engineering spanning to the process scale. Connects theory to real-world applications in research or industry settings. Offered: jointly with CHEM E 545; A.

CHEM 546 Software Engineering for Molecular Science and Engineering (3)
Introduces basic principles of scientific software development in Python in the context of project-based work for molecular science and engineering spanning to the process scale. Covers command line tools, Python from the perspective of molecular and process engineering methods, software design, and development and collaboration principles (e.g., version control). Course overlaps with: CSE 583. Offered: jointly with CHEM E 546; W.

CHEM 547 Data Science Capstone Project (3)
Involves teams of graduate students from molecular, materials or clean energy focused disciplines working on Data Science oriented research and engineering projects solicited from internal and external partners. Employ modern team-based software engineering principles and cutting edge Data Science methods, including but not limited to machine learning, statistics, visualization and data management. Prerequisite: CHEM E 545/CHEM 545 and CHEM E 546/CHEM 546; recommended: prior exposure to data science fundamentals and software development. Offered: jointly with CHEM E 547; Sp.

CHEM 550 Quantum Mechanics of Atoms and Molecules (3)
Origins and basic postulates of quantum mechanics, solutions to single-particle problems, angular momentum and hydrogenic wave functions, matrix methods, perturbation theory, variational methods. Offered: A.

CHEM 551 Quantum Dynamics and Spectroscopy (3)
Fundamental theory of spectroscopy and quantum dynamics; vibrational, electronic, X-ray and magnetic resonance spectroscopies; and application examples from current scientific literature. Prerequisite: CHEM 550. Offered: W.

CHEM 552 Statistical Mechanics (3)
General theorems of statistical mechanics, relation of the equilibrium theory to classical thermodynamics, Legendre transformations, quantum statistics, theory of imperfect gases, lattice statistics, and theory of solids. Prerequisite: CHEM 550. Offered: Sp.

CHEM 553 Advanced Statistical Mechanics (3)
Advanced topics in equilibrium and nonequilibrium statistical mechanics. Prerequisite: CHEM 552. Offered: Sp.

CHEM 560 Current Problems in Physical Chemistry (1-3, max. 12)
Primarily for doctoral candidates in physical chemistry. A discussion of topics selected from active research fields. See department for instructor and the topic during any particular quarter.

CHEM 561 Introduction to Quantum Information Science and Engineering for Chemists and Materials Scientists (3)
Introduction to the core concepts of quantum information science and engineering including mathematical and quantum mechanical foundations, qubits, coherence, entanglement, applications, and materials systems Prerequisite: CHEM 455 or CHEM 475. Offered: jointly with MSE 561; A.

CHEM 565 Computational Chemistry (3)
Basics of molecular quantum chemistry (Hartree-Fock and density functional theory); numerical implementation using computers, including basics of programming and scientific computing; applications to problems in chemistry; use of computational chemistry software packages to study chemical reactions and molecular properties. Offered: W.

CHEM 566 Energy Materials, Devices, and Systems (3)
Provides project-based training for synthesis and characterization of new energy materials for generation and storage and integrating renewables into energy systems. Employs instruments at the Clean Energy Research Training Testbeds, a UW user facility. Topics include nanoparticle synthesis, solar cell and module characterization, coin cell battery assembly and testing, photochemistry, 2D semiconductors, and grid simulation. Offered: jointly with CHEM E 540/MSE 566/PHYS 566; A.

CHEM 567 Computers in Data Acquisition and Analysis (3)
Interface computers to a variety of laboratory equipment such as Geiger Counter, pH titration, spectrophotometer, PID controlled magnetic induction device, or an acoustic tube. Students will individually interface the computer to the equipment, write the code to drive the experiment, and analyze or model the data. Utilizes LabView, Matlab, Octave Offered: Sp.

CHEM 571 Current Research Topics in Inorganic Chemistry (1, max. 18)
Focused discussion of ongoing research occurring across the department in the area of Inorganic Chemistry Credit/no-credit only. Offered: AWSp.

CHEM 573 Current Research Topics in Organic and Biological Chemistry (1, max. 18)
Discussion of ongoing research occurring in organic chemistry and chemical biology. Offered: AWSp.

CHEM 574 Current Research Topics in Spectroscopy (1, max. 18)
Ongoing research in the area of spectroscopy. Offered: AWSp.

CHEM 575 Current Research Topics in Theoretical and Computational Chemistry (1, max. 18)
Focused discussion of ongoing research occurring across the department in the area of theoretical and computational chemistry. Offered: AWSp.

CHEM 578 Current Research Topics in Materials Chemistry (1, max. 18)
Focused ongoing research in Materials Chemistry. Credit/no-credit only. Offered: AWSp.

CHEM 581 Preparation for Second-Year Exam (3-, max. 9)
Preparation for examination. Open only to students accepted for doctoral work in chemistry, in their second year of study. Credit/no-credit only. Offered: AWSp.

CHEM 584 Electronic and Optoelectronic Polymers (3)
Covers the chemistry, physics, materials science, and applications of semiconducting and metallic conjugated polymers. Examines the structural origins of the diverse electronic and optoelectronic properties of conjugated polymers. Exemplifies applications by light-emitting diodes, lasers, solar cells, thin film transistors, electrochromic devices, biosensors, and batteries. Prerequisite: either CHEM 453, CHEM 455, or equivalent background. Offered: A.

CHEM 585 Electronic Structure and Application of Materials (3)
Introduction to electronic structure theory of solids from a chemical perspective, including band theory and the free electron model, with an emphasis on modern trends in research in inorganic materials in the bulk and on the nanometer scale. Recommended: familiarity with particle in a box; free electron model; symmetry and symmetry elements; molecular orbital theory; principles of inorganic chemistry; and ability to independently research and learn advanced topics. Offered: W.

CHEM 586 Electronic Dynamics in Organic and Inorganic Materials (3)
Energy and charge transfer; exciton migration and charge transport; photophysical dynamics in optoelectronic and kinetic processes in electrochemical energy conversion. Recommended: working knowledge of electromagnetism; calculus; differential equations; and linear algebra. Offered: Sp.

CHEM 587 Nanomaterials Chemistry and Engineering (3)
Rigorous overview of fundamental chemical and physical concepts important to nanomaterials science and engineering. Focus on luminescent, plasmonic, magnetic nanomaterials. Students will learn basic concepts prevalent in the nanomaterials literature, and develop rigorous mathematical understanding of fundamental principles that govern many of the advanced materials that are currently under development in the field. Prerequisite: CHEM 455; MATH 207; and CHEM E 326; recommended: classical physics, quantum mechanics, thermodynamics, and ordinary and partial differential equations Offered: jointly with CHEM E 535; Sp.

CHEM 590 Seminar in General Chemistry (1, max. 18)
For chemistry graduate students only. Credit/no-credit only. Offered: AWSp.

CHEM 591 Seminar in Inorganic Chemistry (1, max. 18)
For chemistry graduate students only. Credit/no-credit only. Offered: AWSp.

CHEM 592 Seminar in Analytical Chemistry (1, max. 18)
For chemistry graduate students only. Credit/no-credit only. Offered: AWSp.

CHEM 593 Seminar in Organic Chemistry (1, max. 18)
For chemistry graduate students only. Credit/no-credit only. Offered: AWSp.

CHEM 595 Seminar in Physical Chemistry (1, max. 18)
Credit/no-credit only. Offered: AWSp.

CHEM 597 Seminar in Molecular Engineering (1, max. 30)
Weekly seminars on current topics in molecular Engineering. Credit/no-credit only. Offered: jointly with MOLENG 520; AWSp.

CHEM 600 Independent Study or Research (*-)
Prerequisite: permission of coordinator. Offered: AWSpS.

CHEM 700 Master's Thesis (*-)
Prerequisite: permission of coordinator. Offered: AWSpS.

CHEM 800 Doctoral Dissertation (*-)
Prerequisite: permission of coordinator. Offered: AWSpS.